By Whitney Alexandra Hutchinson-Gilford syndrome HGPS is a rare and progressive disorder that causes children to age prematurely, often with an onset within the first few years of their life.
This disorder is passed through parental genes to a child. This particular mutation causes the body to incorrectly produce a protein needed for the nucleus of a cell to stay together. As a result, the cells in the body of individuals with this condition are unstable, and this abnormality leads hutchinson gilford syndrome rapid aging. The life expectancy of a Hutchinson-Gilford syndrome patient is thirteen years on average, but some may live up to twenty years.
Strokes or cardiovascular problems are commonly the cause of death in affected individuals. Children with this syndrome often appear normal when they are born, but symptoms begin to appear between ten and twenty-four months old in most cases.
Learn about the major symptoms of Hutchinson-Gilford syndrome now. Within the first year of the child's life, however, they will experience stagnation in growth.
They will gain less weight and will be much shorter for their age then they should be. Children affected by this condition will have no body fat and very little muscle. Between the ages of eighteen months and two years, the child will become very thin and have a larger head than normal.
The child's primary teeth will come in several years later than usual. The growth of the child will slow down as their cells fail to duplicate at a regular rate. Functional laminins A and C are required for the cell's filamentous lamina to replicate DNA accurately, structurally support the nucleolus, and correctly hutchinson gilford syndrome RNA. When hutchinsob cells inside of the tissues cannot replicate, the tissues of the body will fail to grow.
Continue reading to article source more Hutchinson-Gilford syndrome symptoms now. Distinctive Facial Appearance NCStateUniversity Children affected by Hutchinson-Gilford syndrome will develop a distinctive facial appearance that looks considerably different than the face of a healthy child. Affected children often have a head that is larger in terms of hutchinson gilford syndrome to the size of their face.
They also tend to have a lower jaw that is disproportionately small to the size of their head. Other common facial characteristics of children with Hutchinson-Gilford syndrome are a beaked nose, thin lips, and a face that hutchinson gilford syndrome narrower than it should. The child's eyes sometimes abnormally protrude outward, and their eyelids may not eyndrome completely. Due to an underdeveloped jaw or micrognathia, Hutchinson-Gilford syndrome patients often have an abnormal crowding of the teeth once they erupt into the mouth. In addition, these individuals often develop a slight blueness surrounding their mouth.]